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    Saturday, 13 February 2016

    Calcium : Commonly used drugs in Emergency & ICU




    Calcium

    Trade name: Calciday, Caltrate
    Class: Electrolyte, mineral Calcium Salts
    Pregnancy: (Category B)
    Action:
    §  It is essential for maintenance of normal function of nerves, muscles, skeletal system & permeability of cell membranes & capillaries.
    §  Necessary for activation of many  enzymes, contraction  of cardiac, skeletal & smooth muscles, never impulses, respiration, and  blood  coagulation. Uses:
    *  I.V:
    §  Acute hypocalcemic tetany secondary to : § Renal failure § Hypoparathyroidism.
    §  Premature infants.
    §  To treat depletion of electrolytes.
    §  During cardiac resuscitation.
    *  I.M. or I.V:
          To reduce spasm (renal & intestinal).
          To relief sensitivity reactions of insect bites.
    ** P.O:
    §  Chronic hypoparathyroidism. § Osteoporosis § Osteomalacia.
    §  Rickets
    §  Myasthenia gravis
    §  Supplement for pregnant women.
    Dose
    §  In hypocalcaemic tetany an initial intravenous injection of 10 mL (2.25 mmol) of calcium gluconate injection 10% should be followed by the continuous infusion of about 40 mL (9 mmol) daily, but plasma calcium should be monitored.
    §  This regimen can also be used immediately to temporarily reduce the toxic effects of hyperkalaemia.
    §  Maintenance: calcium gluconate 1–2 g daily.
    Contraindications:
          Digitized patients.
          Some renal & cardiac patients.
          Cancer with bone metastasis.
    Side effects:
    §  Hypercalceia  characterized by lassitude – fatigue, skeletal muscle weakness, confusion & constipation.
    §  Renal calculi, bradycardia, arrhythmias & renal impairment.
    §  Rapid I.V. administration. May result in vasodilatation, decreased B.P. & H.R., cardiac arrhythmias, syncope and cardiac arrest.
    Nursing considerations:
    Oral:
          administer 1-1.5 hr after meals, alkalis & large amounts of fat decrease the absorption of calcium.
          If the client has difficulty swallowing large tablets, obtain a calcium in watersuspension by diluting the calcium in hot water then cooled by administration. I.V:
          Administer slowly.
          Observe vital signs closely for evidence of bradycardia & hypotension.
          Prevent any leakage of medication into the tissue since it is extremely irritating.
            I.M:
          Rotate the injection sites.
          Obtain baseline renal function.

          In case of hypocalcemic tetany, provide safety precautions to prevent injury.
    Item Reviewed: Calcium : Commonly used drugs in Emergency & ICU Rating: 5 Reviewed By: Dr.MosabNajjar
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