Ceftazidime :
Trade name: Ceptaz, Fortum, Tazicef, Tazidime
Class: Antibiotic "cephalosporines" third-generation Pregnancy:
(Category B)
Action : Bind to bacterial cell wall membrane,
causing cell death.
Uses:
Ceftazidime eliminates bacteria that cause many kinds of
infections, including lung, skin,
bone, joint, stomach, blood, gynecological, and urinary tract
infections
Dose
by deep intramuscular
injection or intravenous injection or infusion, 1 g every 8
hours or 2 g every 12 hours; 2 g every 8–12 hours or 3 g every 12 hours in severe infections; single doses over 1 g intravenous
route only; elderly usual max. 3 g daily; child up to 2 months 25–60 mg/kg daily in 2 divided doses, over
2 months 30–100 mg/kg daily in 2–3 divided doses; up to 150 mg/kg daily
(max. 6 g daily) in 3 divided doses if immunocompromised
or meningitis; intravenous route recommended for children
Urinary-tract
and less serious infections, 0.5–1 g every 12 hours
Pseudomonal lung
infection in cystic fibrosis, adult 100–150 mg/kg daily in 3 divided doses; child up to 150 mg/kg daily (max. 6 g daily) in
3divided doses; intravenous route recommended for children
Surgical
prophylaxis, prostatic surgery, 1 g at induction of anesthesia
repeated if necessary when catheter removed Contraindications:
• Hypersensitivity to cephalosporin
Side effects:
• Diarrhea, stomach pain, upset stomach, vomiting.
Nursing
considerations:
§ Infuse over 30 minutes unless otherwise indicated.
§ Therapy should be continued for at least 2-3 days after symptoms
of infection have disappeared.
§ Assess client with a history of hypersensitivity reaction. “for
penicillin or cephalosporin.”
§ Assess client financial status. These drugs are usually
expensive.
§ Obtain
liver & renal studies.
